There’s nothing quite like a home-cooked meal that delivers on both comfort and flavor with minimal effort. This Melt-In-Your-Mouth Chicken is exactly that—a simple yet incredibly delicious dish that requires just a handful of ingredients. With tender, juicy chicken baked in a creamy, flavorful coating, this recipe is perfect for busy weeknights, cozy family dinners, or even a meal prep staple that everyone will love.
If you’ve ever struggled to keep chicken breast from drying out, this recipe will change everything. The secret lies in a rich, tangy, and slightly cheesy topping that locks in moisture and infuses the chicken with irresistible flavor. The result? Chicken so tender and juicy that it practically melts in your mouth!
Why You’ll Love This Recipe
- Super Easy to Make: With just a few minutes of prep, the oven does all the work for you.
- Incredibly Tender and Juicy: The creamy coating keeps the chicken moist and flavorful.
- Crowd-Pleasing Flavor: A perfect balance of creamy, tangy, and savory goodness.
- Minimal Ingredients: You probably have most of these items in your kitchen already!
- Great for Meal Prep: This dish reheats beautifully, making it perfect for leftovers.

Ingredients You’ll Need
- 4 boneless, skinless chicken breasts
- 1 cup mayonnaise
- ½ cup plain Greek yogurt
- ½ cup grated Parmesan cheese
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1 teaspoon paprika
- ½ teaspoon salt
- ½ teaspoon black pepper

How to Make Melt-In-Your-Mouth Chicken
Step-by-Step Instructions
Step 1: Preheat the Oven
Preheat your oven to 375°F (190°C). Lightly grease a baking dish or line it with parchment paper to prevent sticking.
Step 2: Prepare the Chicken
Pat the chicken breasts dry with a paper towel. This helps the creamy coating stick better and ensures even cooking. If your chicken breasts are very thick, consider slicing them in half or pounding them slightly to an even thickness.
Step 3: Make the Creamy Coating
In a medium mixing bowl, combine the mayonnaise, Greek yogurt, Parmesan cheese, garlic powder, onion powder, paprika, salt, and black pepper. Stir until well blended. This mixture will create a flavorful and moisture-sealing crust on the chicken.
Step 4: Coat the Chicken
Place the chicken breasts in the prepared baking dish. Spread the creamy mixture evenly over each piece, making sure to fully cover the tops.
Step 5: Bake to Perfection
Bake uncovered for 35-40 minutes, or until the chicken is cooked through and reaches an internal temperature of 165°F (75°C). The top should be golden brown and slightly crispy.
Step 6: Let It Rest & Serve
Once done, remove the chicken from the oven and let it rest for 5 minutes before serving. This helps retain all the juices, making every bite extra tender and delicious.

Helpful Tips
- Use an Instant-Read Thermometer: This ensures your chicken is cooked to perfection without drying out.
- Don’t Skip the Resting Time: Allowing the chicken to sit for a few minutes after baking helps the juices redistribute, keeping it moist.
- Try Different Cheeses: While Parmesan adds a delicious nutty flavor, you can also experiment with shredded mozzarella or cheddar for a different taste.
- Add Some Heat: If you like a little spice, sprinkle some cayenne pepper or red pepper flakes into the mixture.
- Use Chicken Thighs: If you prefer dark meat, boneless skinless chicken thighs work beautifully in this recipe.
Recipe Details
- Prep Time: 10 minutes
- Cook Time: 35-40 minutes
- Total Time: 45-50 minutes
- Yield: 4 servings
- Category: Dinner
- Method: Baking
- Cuisine: American
- Diet: High-Protein

Notes
- You can substitute sour cream for Greek yogurt if you prefer a richer flavor.
- For an even crispier topping, broil the chicken for the last 2-3 minutes of baking.
- This recipe pairs well with roasted vegetables, mashed potatoes, or a simple green salad.
Nutritional Information (Approximate per serving)
- Calories: 350
- Protein: 38g
- Carbohydrates: 2g
- Fat: 20g
- Saturated Fat: 6g
- Cholesterol: 110mg
- Sodium: 480mg
Frequently Asked Questions
Can I use something other than mayonnaise?
Yes! If you’re not a fan of mayo, you can replace it with more Greek yogurt or use sour cream instead. The texture will still be creamy, but the flavor will be slightly tangier.
Can I make this ahead of time?
Absolutely! You can prepare the chicken and creamy mixture ahead of time and store it in the fridge for up to 24 hours before baking. Just pop it in the oven when you’re ready to cook!
Can I freeze Melt-In-Your-Mouth Chicken?
Yes! Once baked and cooled, store leftovers in an airtight container and freeze for up to 3 months. Reheat in the oven at 350°F (175°C) until warmed through.
What should I serve with this dish?
This chicken pairs wonderfully with roasted vegetables, rice, garlic mashed potatoes, or even a fresh side salad for a lighter option.
Storage Instructions
- Refrigerate: Store leftovers in an airtight container in the fridge for up to 4 days.
- Freeze: Place cooled chicken in a freezer-safe container or ziplock bag and freeze for up to 3 months.
- Reheat: Warm in the oven at 350°F (175°C) for about 10-15 minutes, or microwave in short intervals to avoid drying out.

Related Recipes
If you loved this Melt-In-Your-Mouth Chicken, here are a few other creamy, comforting chicken dishes you might enjoy:
- Melt-in-Your-Mouth Caesar Chicken
- Homemade Chicken Alfredo Crazy Puffs – A Little Caesars-Inspired
- Melt-In-Your-Mouth Chicken Breast
- Melt-in-Your-Mouth Chicken
Conclusion
This Melt-In-Your-Mouth Chicken is the perfect dish when you need something easy, delicious, and satisfying. Whether you’re cooking for your family, meal prepping for the week, or just looking for a comforting dinner, this recipe will never disappoint. Give it a try, and don’t be surprised if it becomes a regular on your menu!
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Melt-In-Your-Mouth Chicken
Description
There’s nothing quite like a home-cooked meal that delivers on both comfort and flavor with minimal effort. This Melt-In-Your-Mouth Chicken is exactly that—a simple yet incredibly delicious dish that requires just a handful of ingredients. With tender, juicy chicken baked in a creamy, flavorful coating, this recipe is perfect for busy weeknights, cozy family dinners, or even a meal prep staple that everyone will love.
If you’ve ever struggled to keep chicken breast from drying out, this recipe will change everything. The secret lies in a rich, tangy, and slightly cheesy topping that locks in moisture and infuses the chicken with irresistible flavor. The result? Chicken so tender and juicy that it practically melts in your mouth!
Ingredients
- 4 boneless, skinless chicken breasts
- 1 cup mayonnaise
- ½ cup plain Greek yogurt
- ½ cup grated Parmesan cheese
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1 teaspoon paprika
- ½ teaspoon salt
- ½ teaspoon black pepper
Instructions
Preheat your oven to 375°F (190°C). Lightly grease a baking dish or line it with parchment paper to prevent sticking.
Pat the chicken breasts dry with a paper towel. This helps the creamy coating stick better and ensures even cooking. If your chicken breasts are very thick, consider slicing them in half or pounding them slightly to an even thickness.
In a medium mixing bowl, combine the mayonnaise, Greek yogurt, Parmesan cheese, garlic powder, onion powder, paprika, salt, and black pepper. Stir until well blended. This mixture will create a flavorful and moisture-sealing crust on the chicken.
Place the chicken breasts in the prepared baking dish. Spread the creamy mixture evenly over each piece, making sure to fully cover the tops.
Bake uncovered for 35-40 minutes, or until the chicken is cooked through and reaches an internal temperature of 165°F (75°C). The top should be golden brown and slightly crispy.
Once done, remove the chicken from the oven and let it rest for 5 minutes before serving. This helps retain all the juices, making every bite extra tender and delicious.
Notes
- You can substitute sour cream for Greek yogurt if you prefer a richer flavor.
- For an even crispier topping, broil the chicken for the last 2-3 minutes of baking.
- This recipe pairs well with roasted vegetables, mashed potatoes, or a simple green salad.